CATH Classification

Domain Context

CATH Clusters

Superfamily Glycogen Phosphorylase B;
Functional Family Glycosyltransferase

Enzyme Information

2.4.1.115
Anthocyanidin 3-O-glucosyltransferase.
based on mapping to UniProt P51094
UDP-D-glucose + an anthocyanidin = UDP + an anthocyanidin-3-O-beta-D- glucoside.
-!- The anthocyanidin compounds cyanidin, delphinidin, peonidin and to a lesser extent pelargonidin can act as substrates. -!- Does not catalyze glucosylation of the 5-position of cyanidin and does not act on flavanols such as quercetin and kaempferol (cf. EC 2.4.1.91). -!- In conjunction with EC 1.14.20.4, it is involved in the conversion of leucoanthocyanidin into anthocyanidin 3-glucoside. -!- It may act on the pseudobase precursor of the anthocyanidin rather than on the anthocyanidin itself. -!- Formerly EC 2.4.1.233.

UniProtKB Entries (1)

P51094
UFOG_VITVI
Vitis vinifera
Anthocyanidin 3-O-glucosyltransferase 2

PDB Structure

PDB 2C9Z
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of a Flavonoid Glucosyltransferase Reveals the Basis for Plant Natural Product Modification.
Offen, W., Martinez-Fleites, C., Yang, M., Kiat-Lim, E., Davis, B.G., Tarling, C.A., Ford, C.M., Bowles, D.J., Davies, G.J.
Embo J.