CATH Classification

Domain Context

CATH Clusters

Superfamily Calcium-transporting ATPase, cytoplasmic domain N
Functional Family Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type

Enzyme Information
Calcium-transporting ATPase.
based on mapping to UniProt P04191
ATP + H(2)O + Ca(2+)(Side 1) = ADP + phosphate + Ca(2+)(Side 2).
-!- P-type ATPase that undergoes covalent phosphorylation during the transport cycle. -!- This enzyme family comprises three types of Ca(2+)-transporting enzymes that are found in the plasma membrane, the sarcoplasmic reticulum and in Saccharomyces cerevisiae. -!- The first and third transport one ion per ATP hydrolyzed, whereas the second transports two ions. -!- Formerly EC

UniProtKB Entries (1)

Oryctolagus cuniculus
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

PDB Structure

PDB 2C88
External Links
Primary Citation
Modulatory and Catalytic Modes of ATP Binding by the Calcium Pump
Jensen, A.M., Sorensen, T.L., Olesen, C., Moller, J.V., Nissen, P.
Embo J.