CATH Classification

Domain Context

CATH Clusters

Superfamily Glutaredoxin
Functional Family

Enzyme Information

2.5.1.18
Glutathione transferase.
based on mapping to UniProt P30113
RX + glutathione = HX + R-S-glutathione.
-!- A group of enzymes of broad specificity. -!- R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. -!- Also catalyzes the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange. -!- Formerly EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14 and EC 4.4.1.7.

UniProtKB Entries (1)

P30113
GST28_SCHBO
Schistosoma bovis
Glutathione S-transferase class-mu 28 kDa isozyme

PDB Structure

PDB 2C80
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Probing the Mechanism of Gsh Activation in Schistosoma Haematobium Glutathione-S-Transferase by Site-Directed Mutagenesis and X-Ray Crystallography.
Baiocco, P., Gourlay, L.J., Angelucci, F., Fontaine, J., Herve, M., Miele, A.E., Trottein, F., Brunori, M., Bellelli, A.
J.Mol.Biol.