CATH Classification

Domain Context

CATH Clusters

Superfamily Acyl-CoA dehydrogenase/oxidase, N-terminal domain
Functional Family Nitroalkane oxidase

Enzyme Information

1.7.3.1
Nitroalkane oxidase.
based on mapping to UniProt Q8X1D8
A nitroalkane + H(2)O + O(2) = an aldehyde or ketone + nitrite + H(2)O(2).
-!- While nitroethane may be the physiological substrate, the enzyme also acts on several other nitroalkanes, including 1-nitropropane, 2-nitropropane, 1-nitrobutane, 1-nitropentane, 1-nitrohexane, nitrocyclohexane and some nitroalkanols. -!- Differs from EC 1.13.12.16 in that the preferred substrates are neutral nitroalkanes rather than anionic nitronates.

UniProtKB Entries (1)

Q8X1D8
NAO_FUSOX
Fusarium oxysporum
Nitroalkane oxidase

PDB Structure

PDB 2C12
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structures of Nitroalkane Oxidase: Insights Into the Reaction Mechanism from a Covalent Complex of the Flavoenzyme Trapped During Turnover.
Nagpal, A., Valley, M.P., Fitzpatrick, P.F., Orville, A.M.
Biochemistry