CATH Classification

Domain Context

CATH Clusters

Superfamily Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain
Functional Family

Enzyme Information

1.3.5.4
Fumarate reductase (quinol).
based on mapping to UniProt P17412
Succinate + a quinone = fumarate + a quinol.
-!- The enzyme, which is found in anaerobic and facultative organisms such as bacteria, parasitic helminthes, and lower marine organisms, utilizes low potential quinols, such as menaquinol and rhodoquinol, to reduce fumarate as the final step of an anaerobic respiratory chain. -!- The enzyme is known as complex II of the electron transfer chain, similarly to EC 1.3.5.1, to which it is closely related.

UniProtKB Entries (1)

P17596
FRDB_WOLSU
Wolinella succinogenes DSM 1740
Fumarate reductase iron-sulfur subunit

PDB Structure

PDB 2BS2
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Evidence for Transmembrane Proton Transfer in a Dihaem-Containing Membrane Protein Complex.
Madej, M.G., Nasiri, H.R., Hilgendorff, N.S., Schwalbe, H., Lancaster, C.R.D.
Embo J.