CATH Classification

Domain Context

CATH Clusters

Superfamily Creatinase/methionine aminopeptidase superfamily
Functional Family Xaa-Pro aminopeptidase 3

Enzyme Information

3.4.11.9
Xaa-Pro aminopeptidase.
based on mapping to UniProt P15034
Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide.
-!- Generally membrane bound enzyme present in both mammalian and bacterial cells. -!- Belongs to peptidase family M24B.

UniProtKB Entries (1)

P15034
AMPP_ECOLI
Escherichia coli K-12
Xaa-Pro aminopeptidase

PDB Structure

PDB 2BN7
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural and Functional Implications of Metal Ion Selection in Aminopeptidase P, a Metalloprotease with a Dinuclear Metal Center.
Graham, S.C., Bond, C.S., Freeman, H.C., Guss, J.M.
Biochemistry