CATH Classification

Domain Context

CATH Clusters

Superfamily Protein tyrosine phosphatase superfamily
Functional Family Tyrosine-protein phosphatase non-receptor type 5

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt P54829
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

P54829
PTN5_HUMAN
Homo sapiens
Tyrosine-protein phosphatase non-receptor type 5

PDB Structure

PDB 2BIJ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatases.
Eswaran, J., von Kries, J.P., Marsden, B., Longman, E., Debreczeni, J.E., Ugochukwu, E., Turnbull, A., Lee, W.H., Knapp, S., Barr, A.J.
Biochem. J.