CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family Aurora kinase A

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q6DE08
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

Q6DE08
AUKBA_XENLA
Xenopus laevis
Aurora kinase B-A

PDB Structure

PDB 2BFX
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Mechanism of Aurora B Activation by Incenp and Inhibition by Hesperadin
Sessa, F., Mapelli, M., Ciferri, C., Tarricone, C., Areces, L.B., Schneider, T.R., Stukenberg, P.T., Musacchio, A.
Mol.Cell