CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Calcium/calmodulin-dependent protein kinase type II subunit delta isoform 2

Enzyme Information

2.7.11.17
Calcium/calmodulin-dependent protein kinase.
based on mapping to UniProt O62305
ATP + a protein = ADP + a phosphoprotein.
-!- Requires calmodulin. -!- A wide range of proteins can act as acceptor, including vimentin, synapsin, glycogen synthase, myosin light-chains and the microtubule- associated tau protein. -!- Not identical with EC 2.7.11.18 or EC 2.7.11.26. -!- Formerly EC 2.7.1.120 and EC 2.7.1.123.

UniProtKB Entries (1)

O62305
KCC2D_CAEEL
Caenorhabditis elegans
Calcium/calmodulin-dependent protein kinase type II

PDB Structure

PDB 2BDW
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of the Autoinhibited Kinase Domain of CaMKII and SAXS Analysis of the Holoenzyme
Rosenberg, O.S., Deindl, S., Sung, R.-J., Nairn, A.C., Kuriyan, J.
Cell(Cambridge,Mass.)