CATH Classification

Domain Context

CATH Clusters

Superfamily Glutaredoxin
Functional Family Protein disulfide-isomerase

Enzyme Information

5.3.4.1
Protein disulfide-isomerase.
based on mapping to UniProt P17967
Catalyzes the rearrangement of -S-S- bonds in proteins.
-!- Needs reducing agents or partly reduced enzyme; the reaction depends on sulfhydryl-disulfide interchange.

UniProtKB Entries (1)

P17967
PDI_YEAST
Saccharomyces cerevisiae S288C
Protein disulfide-isomerase

PDB Structure

PDB 2B5E
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The crystal structure of yeast protein disulfide isomerase suggests cooperativity between its active sites.
Tian, G., Xiang, S., Noiva, R., Lennarz, W.J., Schindelin, H.
Cell(Cambridge,Mass.)