1 keywords

CATH Domain 2b4jC00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.20 Up-down Bundle
Topology 1.20.930 Transcription Elongation Factor S-II; Chain A
Homologous Superfamily 1.20.930.10 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70

Domain Context

CATH Clusters

Superfamily Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
Functional Family

Enzyme Information

UniProtKB Entries (2)

P12497
POL_HV1N5
Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)
Gag-Pol polyprotein
O75475
PSIP1_HUMAN
Homo sapiens
PC4 and SFRS1-interacting protein

PDB Structure

PDB 2B4J
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75
Cherepanov, P., Ambrosio, A.L., Rahman, S., Ellenberger, T., Engelman, A.
Proc.Natl.Acad.Sci.Usa