CATH Classification

Domain Context

CATH Clusters

Superfamily Aconitase, domain 3
Functional Family cytoplasmic aconitate hydratase

Enzyme Information

4.2.1.3
Aconitate hydratase.
based on mapping to UniProt P21399
Citrate = isocitrate.
-!- Besides interconverting citrate and cis-aconitate, it also interconverts cis-aconitate with isocitrate and, hence, interconverts citrate and isocitrate. -!- The equilibrium mixture is 91% citrate, 6% isocitrate and 3% aconitate. -!- Cis-aconitate is used to designate the isomer (Z)-prop-1-ene-1,2,3- tricarboxylate. -!- Formerly EC 4.2.1.4.

UniProtKB Entries (1)

P21399
ACOC_HUMAN
Homo sapiens
Cytoplasmic aconitate hydratase

PDB Structure

PDB 2B3Y
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of human iron regulatory protein 1 as cytosolic aconitase
Dupuy, J., Volbeda, A., Carpentier, P., Darnault, C., Moulis, J.M., Fontecilla-Camps, J.C.
Structure