CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.10190 | BRCT domain |
Domain Context
CATH Clusters
| Superfamily | BRCT domain |
| Functional Family | Mediator of DNA damage checkpoint protein 1 |
Enzyme Information
UniProtKB Entries (1)
| P16104 |
H2AX_HUMAN
Homo sapiens
Histone H2AX
|
PDB Structure
| PDB | 2AZM |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
MDC1 Directly Binds Phosphorylated Histone H2AX to Regulate Cellular Responses to DNA Double-Strand Breaks
Cell(Cambridge,Mass.)
|