CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.600 | Farnesyl Diphosphate Synthase |
|
1.10.600.10 | Farnesyl Diphosphate Synthase |
Domain Context
CATH Clusters
| Superfamily | Farnesyl Diphosphate Synthase |
| Functional Family |
Enzyme Information
| 2.5.1.82 |
Hexaprenyl diphosphate synthase (geranylgeranyl-diphosphate specific).
based on mapping to UniProt Q97W92
Geranylgeranyl diphosphate + 2 isopentenyl diphosphate = 2 diphosphate + all-trans-hexaprenyl diphosphate.
-!- The enzyme prefers geranylgeranyl diphosphate to farnesyl diphosphate as an allylic substrate and does not show activity for geranyl diphosphate and dimethylallyl diphosphate. -!- Formerly EC 2.5.1.33.
|
UniProtKB Entries (1)
| Q97W92 |
HEXPP_SACS2
Saccharolobus solfataricus P2
Hexaprenyl pyrophosphate synthase
|
PDB Structure
| PDB | 2AZJ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Homodimeric hexaprenyl pyrophosphate synthase from the thermoacidophilic crenarchaeon Sulfolobus solfataricus displays asymmetric subunit structures
J.Bacteriol.
|