CATH Classification

Domain Context

CATH Clusters

Superfamily Type I PLP-dependent aspartate aminotransferase-like (Major domain)
Functional Family

Enzyme Information

2.6.1.57
Aromatic-amino-acid transaminase.
based on mapping to UniProt P95468
An aromatic amino acid + 2-oxoglutarate = an aromatic oxo acid + L-glutamate.
-!- L-methionine can also act as donor, more slowly. -!- Oxaloacetate can act as acceptor. -!- Controlled proteolysis converts the enzyme to EC 2.6.1.1.

UniProtKB Entries (1)

P95468
TYRB_PARDE
Paracoccus denitrificans
Aromatic-amino-acid aminotransferase

PDB Structure

PDB 2AY8
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The active site of Paracoccus denitrificans aromatic amino acid aminotransferase has contrary properties: flexibility and rigidity.
Okamoto, A., Ishii, S., Hirotsu, K., Kagamiyama, H.
Biochemistry