CATH Classification

Domain Context

CATH Clusters

Superfamily 2.40.50.100
Functional Family Maltose/maltodextrin import ATP-binding protein MalK

Enzyme Information

7.5.2.1
ABC-type maltose transporter.
based on mapping to UniProt P68187
ATP + H(2)O + maltose-[maltose-binding protein](Side 1) = ADP + phosphate + maltose(Side 2) + [maltose-binding protein](Side 1).
-!- An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. -!- The enzyme, found in bacteria, interacts with an extracytoplasmic substrate binding protein and mediates the import of maltose and maltose oligosaccharides. -!- Formerly EC 3.6.3.19.

UniProtKB Entries (1)

P68187
MALK_ECOLI
Escherichia coli K-12
Maltose/maltodextrin import ATP-binding protein MalK

PDB Structure

PDB 2AWN
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
ATP hydrolysis is required to reset the ATP-binding cassette dimer into the resting-state conformation.
Lu, G., Westbrooks, J.M., Davidson, A.L., Chen, J.
Proc.Natl.Acad.Sci.Usa