CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.30 | Glutaredoxin |
|
3.40.30.10 | Glutaredoxin |
Domain Context
CATH Clusters
| Superfamily | Glutaredoxin |
| Functional Family | NADH-quinone oxidoreductase subunit E |
Enzyme Information
| 1.12.1.3 |
Hydrogen dehydrogenase (NADP(+)).
based on mapping to UniProt Q46505
H(2) + NADP(+) = H(+) + NADPH.
-!- The protein from the bacterium Desulfovibrio fructosovorans exclusively functions as a hydrogen dehydrogenase, while the enzyme from the archaeon Pyrococcus furiosus is part of a heterotetrameric complex where the alpha and delta subunits function as a hydrogenase while the beta and gamma subunits function as sulfur reductase (EC 1.12.98.4). -!- Different from EC 1.12.1.5.
|
UniProtKB Entries (1)
| Q46505 |
HNDA_DESFR
Desulfovibrio fructosivorans
NADP-reducing hydrogenase subunit HndA
|
PDB Structure
| PDB | 2AUV |
| External Links | |
| Method | SOLUTION NMR |
| Organism | Escherichia |
| Primary Citation |
Solution structure of HndAc: a thioredoxin-like domain involved in the NADP-reducing hydrogenase complex
Protein Sci.
|