CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.150 | Vaccinia Virus protein VP39 |
Domain Context
CATH Clusters
| Superfamily | Vaccinia Virus protein VP39 |
| Functional Family | Histamine N-methyltransferase |
Enzyme Information
| 2.1.1.8 |
Histamine N-methyltransferase.
based on mapping to UniProt P50135
S-adenosyl-L-methionine + histamine = S-adenosyl-L-homocysteine + N(tau)- methylhistamine.
|
UniProtKB Entries (1)
| P50135 |
HNMT_HUMAN
Homo sapiens
Histamine N-methyltransferase
|
PDB Structure
| PDB | 2AOX |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structural basis for inhibition of histamine N-methyltransferase by diverse drugs
J.Mol.Biol.
|