CATH Classification

Domain Context

CATH Clusters

Superfamily Dipeptidylpeptidase IV, N-terminal domain
Functional Family Dipeptidyl peptidase 4

Enzyme Information

3.4.14.5
Dipeptidyl-peptidase IV.
based on mapping to UniProt P22411
Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline.
-!- A membrane-bound serine-type peptidase in mammals. -!- EC 3.4.14.11 catalyzes a similar reaction. -!- Belongs to peptidase family S9B.

UniProtKB Entries (1)

P22411
DPP4_PIG
Sus scrofa
Dipeptidyl peptidase 4

PDB Structure

PDB 2AJB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Rigidity and flexibility of dipeptidyl peptidase IV: crystal structures of and docking experiments with DPIV.
Engel, M., Hoffmann, T., Manhart, S., Heiser, U., Chambre, S., Huber, R., Demuth, H.U., Bode, W.
J.Mol.Biol.