CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family | 3-hydroxybutyrate dehydrogenase type 2 |
Enzyme Information
| 1.1.1.- |
With NAD(+) or NADP(+) as acceptor.
based on mapping to UniProt Q9BUT1
|
| 1.1.1.30 |
3-hydroxybutyrate dehydrogenase.
based on mapping to UniProt Q9BUT1
(R)-3-hydroxybutanoate + NAD(+) = acetoacetate + NADH.
-!- Also oxidizes other 3-hydroxymonocarboxylic acids.
|
UniProtKB Entries (1)
| Q9BUT1 |
BDH2_HUMAN
Homo sapiens
3-hydroxybutyrate dehydrogenase type 2
|
PDB Structure
| PDB | 2AG5 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Characterization of human DHRS6, an orphan short chain dehydrogenase/reductase enzyme: a novel, cytosolic type 2 R-beta-hydroxybutyrate dehydrogenase
J.Biol.Chem.
|