CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.2020
Functional Family

Enzyme Information

2.4.2.10
Orotate phosphoribosyltransferase.
based on mapping to UniProt Q9A076
Orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate.
-!- The enzyme from higher eukaryotes also catalyzes the reaction listed as EC 4.1.1.23.

UniProtKB Entries (1)

Q9A076
PYRE_STRP1
Streptococcus pyogenes serotype M1
Orotate phosphoribosyltransferase

PDB Structure

PDB 2AEE
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of Orotate phosphoribosyltransferase from Streptococcus pyogenes
Chang, C., Li, H., Collart, F., Joachimiak, A.
To be Published