CATH Classification

CATH Clusters

Superfamily Carbonic anhydrase
Functional Family Beta carbonic anhydrase 1

Enzyme Information

4.2.1.1
Carbonic anhydrase.
based on mapping to UniProt P45148
H(2)CO(3) = CO(2) + H(2)O.
-!- The enzyme catalyzes the reversible hydration of gaseous CO(2) to carbonic acid, which spontaneously converts to hydrogencarbonate under neutral pH. -!- It is widespread and found in archaea, bacteria, and eukaryotes. -!- Three distinct classes exist, and appear to have evolved independently.

UniProtKB Entries (1)

P45148
CAN_HAEIN
Haemophilus influenzae Rd KW20
Carbonic anhydrase 2

PDB Structure

PDB 2A8C
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Identification of a Novel Noncatalytic Bicarbonate Binding Site in Eubacterial beta-Carbonic Anhydrase
Cronk, J.D., Rowlett, R.S., Zhang, K.Y.J., Tu, C., Endrizzi, J.A., Lee, J., Gareiss, P.C., Preiss, J.R.
Biochemistry