CATH Classification

Domain Context

CATH Clusters

Superfamily Lumazine/riboflavin synthase
Functional Family 6,7-dimethyl-8-ribityllumazine synthase

Enzyme Information

2.5.1.78
6,7-dimethyl-8-ribityllumazine synthase.
based on mapping to UniProt Q9UUB1
1-deoxy-L-glycero-tetrulose 4-phosphate + 5-amino-6- (D-ribitylamino)uracil = 6,7-dimethyl-8-(D-ribityl)lumazine + 2 H(2)O + phosphate.
-!- Involved in riboflavin biosynthesis.

UniProtKB Entries (1)

Q9UUB1
RIB4_SCHPO
Schizosaccharomyces pombe 972h-
6,7-dimethyl-8-ribityllumazine synthase

PDB Structure

PDB 2A58
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural basis of charge transfer complex formation by riboflavin bound to 6,7-dimethyl-8-ribityllumazine synthase
Koch, M., Breithaupt, C., Gerhardt, S., Haase, I., Weber, S., Cushman, M., Huber, R., Bacher, A., Fischer, M.
Eur.J.Biochem.