CATH Classification

CATH Clusters

Superfamily Oxidized Rhodanese, domain 1
Functional Family M-phase inducer phosphatase 2

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt P30305
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

P30305
MPIP2_HUMAN
Homo sapiens
M-phase inducer phosphatase 2

PDB Structure

PDB 2A2K
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Experimental Validation of the Docking Orientation of Cdc25 with Its Cdk2-CycA Protein Substrate.
Sohn, J., Parks, J.M., Buhrman, G., Brown, P., Safi, A., Edelsbrunner, H., Yang, W., Rudolph, J.
Biochemistry