CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleic acid-binding proteins
Functional Family Eukaryotic translation initiation factor 2 subunit alpha

Enzyme Information

UniProtKB Entries (2)

P19525
E2AK2_HUMAN
Homo sapiens
Interferon-induced, double-stranded RNA-activated protein kinase
P20459
IF2A_YEAST
Saccharomyces cerevisiae S288C
Eukaryotic translation initiation factor 2 subunit alpha

PDB Structure

PDB 2A1A
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Higher-Order Substrate Recognition of eIF2alpha by the RNA-Dependent Protein Kinase PKR.
Dar, A.C., Dever, T.E., Sicheri, F.
Cell(Cambridge,Mass.)