CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
Functional Family

Enzyme Information

2.4.2.18
Anthranilate phosphoribosyltransferase.
based on mapping to UniProt P50384
N-(5-phospho-D-ribosyl)-anthranilate + diphosphate = anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate.
-!- In some organisms, this enzyme is part of a multifunctional protein together with one or more components of the system for biosynthesis of tryptophan (EC 4.1.1.48, EC 4.1.3.27, EC 4.2.1.20 and EC 5.3.1.24).

UniProtKB Entries (1)

P50384
TRPD_SACS2
Saccharolobus solfataricus P2
Anthranilate phosphoribosyltransferase

PDB Structure

PDB 1ZXY
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural and mutational analysis of substrate complexation by anthranilate phosphoribosyltransferase from Sulfolobus solfataricus.
Marino, M., Deuss, M., Svergun, D.I., Konarev, P.V., Sterner, R., Mayans, O.
J.Biol.Chem.