CATH Classification

Domain Context

CATH Clusters

Superfamily Endonuclease/exonuclease/phosphatase
Functional Family

Enzyme Information

3.1.4.12
Sphingomyelin phosphodiesterase.
based on mapping to UniProt Q9RLV9
Sphingomyelin + H(2)O = N-acylsphingosine + phosphocholine.
-!- Has very little activity on phosphatidylcholine.

UniProtKB Entries (1)

Q9RLV9
PHLC_LISIV
Listeria ivanovii
Sphingomyelinase C

PDB Structure

PDB 1ZWX
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of SmcL, a bacterial neutral sphingomyelinase C from Listeria.
Openshaw, A.E.A., Race, P.R., Monzo, H.J., Vasquez-Boland, J.A., Banfield, M.J.
J.Biol.Chem.