CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.2020
Functional Family Adenine phosphoribosyltransferase

Enzyme Information

2.4.2.7
Adenine phosphoribosyltransferase.
based on mapping to UniProt P07741
AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate.
-!- 5-amino-4-imidazolecarboxamide can replace adenine.

UniProtKB Entries (1)

P07741
APT_HUMAN
Homo sapiens
Adenine phosphoribosyltransferase

PDB Structure

PDB 1ZN7
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural Complexes of Human Adenine Phosphoribosyltransferase Reveal Novel Features of the APRT Catalytic Mechanism
Silva, C.H., Silva, M., Iulek, J., Thiemann, O.H.
J.Biomol.Struct.Dyn.