CATH Classification

Domain Context

CATH Clusters

Superfamily Zn peptidases
Functional Family Carboxypeptidase B

Enzyme Information

3.4.17.2
Carboxypeptidase B.
based on mapping to UniProt P15086
Preferential release of a C-terminal lysine or arginine amino acid.
-!- Isolated from cattle, pig and dogfish pancreas, and other sources, including skin fibroblasts and adrenal medulla. -!- Belongs to peptidase family M14. -!- Formerly EC 3.4.2.2 and EC 3.4.12.3.

UniProtKB Entries (2)

Q5EPH2
TCI1_RHIBU
Rhipicephalus bursa
Carboxypeptidase inhibitor
P15086
CBPB1_HUMAN
Homo sapiens
Carboxypeptidase B

PDB Structure

PDB 1ZLI
External Links
Method X-RAY DIFFRACTION
Organism Pichia
Primary Citation
The Three-Dimensional Structures of Tick Carboxypeptidase Inhibitor in Complex with A/B Carboxypeptidases Reveal a Novel Double-headed Binding Mode
Arolas, J.L., Popowicz, G.M., Lorenzo, J., Sommerhoff, C.P., Huber, R., Aviles, F.X., Holak, T.A.
J.Mol.Biol.