CATH Domain 1zlhA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.630	Aminopeptidase
	3.40.630.10	Zn peptidases

Domain Context

CATH Clusters

Superfamily	Zn peptidases
Functional Family	Carboxypeptidase A1

Enzyme Information

3.4.17.1

Carboxypeptidase A.

based on mapping to UniProt P00730

Release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.

-!- Isolated from cattle, pig and dogfish pancreas, and other sources including mast cells and skeletal muscle. -!- Belongs to peptidase family M14. -!- Formerly EC 3.4.2.1 and EC 3.4.12.2.

UniProtKB Entries (2)

P00730	CBPA1_BOVIN Bos taurus Carboxypeptidase A1
Q5EPH2	TCI1_RHIBU Rhipicephalus bursa Carboxypeptidase inhibitor

PDB Structure

PDB	1ZLH
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Pichia
Primary Citation	The Three-Dimensional Structures of Tick Carboxypeptidase Inhibitor in Complex with A/B Carboxypeptidases Reveal a Novel Double-headed Binding Mode Arolas, J.L., Popowicz, G.M., Lorenzo, J., Sommerhoff, C.P., Huber, R., Aviles, F.X., Holak, T.A. J.Mol.Biol.