CATH Classification

Domain Context

CATH Clusters

Superfamily Zn peptidases
Functional Family Carboxypeptidase A1

Enzyme Information

3.4.17.1
Carboxypeptidase A.
based on mapping to UniProt P00730
Release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.
-!- Isolated from cattle, pig and dogfish pancreas, and other sources including mast cells and skeletal muscle. -!- Belongs to peptidase family M14. -!- Formerly EC 3.4.2.1 and EC 3.4.12.2.

UniProtKB Entries (2)

P00730
CBPA1_BOVIN
Bos taurus
Carboxypeptidase A1
Q5EPH2
TCI1_RHIBU
Rhipicephalus bursa
Carboxypeptidase inhibitor

PDB Structure

PDB 1ZLH
External Links
Method X-RAY DIFFRACTION
Organism Pichia
Primary Citation
The Three-Dimensional Structures of Tick Carboxypeptidase Inhibitor in Complex with A/B Carboxypeptidases Reveal a Novel Double-headed Binding Mode
Arolas, J.L., Popowicz, G.M., Lorenzo, J., Sommerhoff, C.P., Huber, R., Aviles, F.X., Holak, T.A.
J.Mol.Biol.