CATH Classification

Domain Context

CATH Clusters

Superfamily L27 domain
Functional Family

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt O14936
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (2)

P90976
P90976_CAEEL
Caenorhabditis elegans
LIN-7
O14936
CSKP_HUMAN
Homo sapiens
Peripheral plasma membrane protein CASK

PDB Structure

PDB 1ZL8
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
A General Model for Preferential Hetero-oligomerization of LIN-2/7 Domains: Mechanism Underlying Directed Assembly of Supramolecular Signaling Complexes
Petrosky, K.Y., Ou, H.D., Lohr, F., Dotsch, V., Lim, W.A.
J.Biol.Chem.