CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.1280.10
Functional Family tRNA (guanosine(18)-2'-O)-methyltransferase

Enzyme Information

2.1.1.34
tRNA (guanosine(18)-2'-O)-methyltransferase.
based on mapping to UniProt O67577
S-adenosyl-L-methionine + guanosine(18) in tRNA = S-adenosyl-L- homocysteine + 2'-O-methylguanosine(18) in tRNA.
-!- The enzyme catalyzes the methylation of guanosine(18) in tRNA.

UniProtKB Entries (1)

O67577
TRMH_AQUAE
Aquifex aeolicus VF5
TRNA (guanosine(18)-2'-O)-methyltransferase

PDB Structure

PDB 1ZJR
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of a class II TrmH tRNA-modifying enzyme from Aquifex aeolicus.
Pleshe, E., Truesdell, J., Batey, R.T.
Acta Crystallogr.,Sect.F