CATH Classification

Domain Context

CATH Clusters

Superfamily PK beta-barrel domain-like
Functional Family

Enzyme Information

2.7.1.40
Pyruvate kinase.
based on mapping to UniProt P14618
ATP + pyruvate = ADP + phosphoenolpyruvate.
-!- UTP, GTP, CTP, ITP and dATP can also act as donors. -!- Also phosphorylates hydroxylamine and fluoride in the presence of CO(2).

UniProtKB Entries (1)

P14618
KPYM_HUMAN
Homo sapiens
Pyruvate kinase PKM

PDB Structure

PDB 1ZJH
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of human muscle pyruvate kinase (PKM2).
Atanassova, A., Choe, J., Arrowsmith, C., Edwards, A., Sundstrom, M., Bochkarev, A., Park, H.
TO BE PUBLISHED