CATH Classification

Domain Context

CATH Clusters

Superfamily Alkaline Phosphatase, subunit A
Functional Family Alkaline phosphatase

Enzyme Information

3.1.3.1
Alkaline phosphatase.
based on mapping to UniProt P05187
A phosphate monoester + H(2)O = an alcohol + phosphate.
-!- Active at a high pH optimum. -!- Wide specificity. -!- Also catalyzes transphosphorylations. -!- Some enzymes hydrolyze diphosphate (cf. EC 3.6.1.1).

UniProtKB Entries (1)

P05187
PPB1_HUMAN
Homo sapiens
Alkaline phosphatase, placental type

PDB Structure

PDB 1ZEF
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Studies of Human Placental Alkaline Phosphatase in Complex with Functional Ligands.
Llinas, P., Stura, E.A., Menez, A., Kiss, Z., Stigbrand, T., Millan, J.L., Le Du, M.H.
J.Mol.Biol.