CATH Domain 1z4uA03

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.70	Alpha-Beta Plaits
	3.30.70.270	Reverse transcriptase/Diguanylate cyclase domain

Domain Context

CATH Clusters

Superfamily	3.30.70.270
Functional Family

Enzyme Information

UniProtKB Entries (1)

O93077_9HEPC

Hepacivirus C

Genome polyprotein

PDB Structure

PDB	1Z4U
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Inhibitors of HCV NS5B polymerase. Part 2: Evaluation of the northern region of (2Z)-2-benzoylamino-3-(4-phenoxy-phenyl)-acrylic acid Pfefferkorn, J.A., Nugent, R., Gross, R.J., Greene, M., Mitchell, M.A., Reding, M.T., Funk, L.A., Anderson, R., Wells, P.A., Shelly, J.A., Anstadt, R., Finzel, B.C., Harris, M.S., Kilkuskie, R.E., Kopta, L.A., Schwende, F.J. Bioorg.Med.Chem.Lett.