CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.630 | Aminopeptidase |
|
3.40.630.10 | Zn peptidases |
Domain Context
CATH Clusters
| Superfamily | Zn peptidases |
| Functional Family | Succinylglutamate desuccinylase |
Enzyme Information
| 3.5.1.96 |
Succinylglutamate desuccinylase.
based on mapping to UniProt P76215
N-succinyl-L-glutamate + H(2)O = succinate + L-glutamate.
-!- N(2)-acetylglutamate is not a substrate. -!- The final enzyme in the arginine succinyltransferase (AST) pathway for the catabolism of arginine. -!- This pathway converts the carbon skeleton of arginine into glutamate, with the concomitant production of ammonia and conversion of succinyl-CoA into succinate and CoA. -!- The five enzymes involved in this pathway are EC 2.3.1.109, EC 3.5.3.23, EC 2.6.1.11, EC 1.2.1.71 and EC 3.5.1.96.
|
UniProtKB Entries (1)
| P76215 |
ASTE_ECOLI
Escherichia coli K-12
Succinylglutamate desuccinylase
|
PDB Structure
| PDB | 1YW6 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal Structure of Succinylglutamate Desuccinylase from Escherichia coli, Northeast Structural Genomics Target ET72.
To be Published
|