CATH Classification

Domain Context

CATH Clusters

Superfamily HRDC domain
Functional Family Ribonuclease D

Enzyme Information

3.1.13.5
Ribonuclease D.
based on mapping to UniProt P09155
Exonucleolytic cleavage that removes extra residues from the 3'-terminus of tRNA to produce 5'-mononucleotides.
-!- Alteration of the 3'-terminal base has no effect on the rate of hydrolysis whereas modification of the 3'-terminal sugar has a major effect. -!- tRNA terminating with a 3'-phosphate is completely inactive. -!- This enzyme can convert a tRNA precursor into a mature tRNA.

UniProtKB Entries (1)

P09155
RND_ECOLI
Escherichia coli K-12
Ribonuclease D

PDB Structure

PDB 1YT3
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal Structure of Escherichia coli RNase D, an Exoribonuclease Involved in Structured RNA Processing
Zuo, Y., Wang, Y., Malhotra, A.
Structure