CATH Classification

Domain Context

CATH Clusters

Superfamily Blc2-like
Functional Family Bcl-2-like protein 1

Enzyme Information

UniProtKB Entries (1)

Q07817
B2CL1_HUMAN
Homo sapiens
Bcl-2-like protein 1

PDB Structure

PDB 1YSN
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
An inhibitor of Bcl-2 family proteins induces regression of solid tumours
Oltersdorf, T., Elmore, S.W., Shoemaker, A.R., Armstrong, R.C., Augeri, D.J., Belli, B.A., Bruncko, M., Deckwerth, T.L., Dinges, J., Hajduk, P.J., Joseph, M.K., Kitada, S., Korsmeyer, S.J., Kunzer, A.R., Letai, A., Li, C., Mitten, M.J., Nettesheim, D.G., Ng, S., Nimmer, P.M., O'Connor, J.M., Oleksijew, A., Petros, A.M., Reed, J.C., Shen, W., Tahir, S.K., Thompson, C.B., Tomaselli, K.J., Wang, B., Wendt, M.D., Zhang, H., Fesik, S.W., Rosenberg, S.H.
Nature