CATH Classification

Domain Context

CATH Clusters

Superfamily Rhodanese-like domain
Functional Family M-phase inducer phosphatase 2

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt P30305
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

P30305
MPIP2_HUMAN
Homo sapiens
M-phase inducer phosphatase 2

PDB Structure

PDB 1YS0
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural Mechanism of Oxidative Regulation of the Phosphatase Cdc25B via an Intramolecular Disulfide Bond
Buhrman, G.K., Parker, B., Sohn, J., Rudolph, J., Mattos, C.
Biochemistry