CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Anionic trypsin

Enzyme Information

3.4.21.4
Trypsin.
based on mapping to UniProt P00763
Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.
-!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.4.

UniProtKB Entries (2)

P00763
TRY2_RAT
Rattus norvegicus
Anionic trypsin-2
P00974
BPT1_BOVIN
Bos taurus
Pancreatic trypsin inhibitor

PDB Structure

PDB 1YLC
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Partially folded bovine pancreatic trypsin inhibitor analogues attain fully native structures when co-crystallized with S195A rat trypsin
Getun, I.V., Brown, C.K., Tulla-Puche, J., Ohlendorf, D., Woodward, C., Barany, G.
J.Mol.Biol.