CATH Classification

Domain Context

CATH Clusters

Superfamily Protein tyrosine phosphatase superfamily
Functional Family receptor-type tyrosine-protein phosphatase C isoform X1

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt P08575
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (2)

P03077
MT_POVMA
Murine polyomavirus strain A2
Middle T antigen
P08575
PTPRC_HUMAN
Homo sapiens
Receptor-type tyrosine-protein phosphatase C

PDB Structure

PDB 1YGU
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural basis for the function and regulation of the receptor protein tyrosine phosphatase CD45.
Nam, H.J., Poy, F., Saito, H., Frederick, C.A.
J.Exp.Med.