CATH Classification

Domain Context

CATH Clusters

Superfamily Jelly Rolls
Functional Family

Enzyme Information

1.13.11.6
3-hydroxyanthranilate 3,4-dioxygenase.
based on mapping to UniProt Q1LCS4
3-hydroxyanthranilate + O(2) = 2-amino-3-carboxymuconate semialdehyde.
-!- The product of the reaction spontaneously rearrange to quinolinic acid (quin). -!- Formerly EC 1.13.1.6.

UniProtKB Entries (1)

Q1LCS4
3HAO_CUPMC
Cupriavidus metallidurans CH34
3-hydroxyanthranilate 3,4-dioxygenase

PDB Structure

PDB 1YFW
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural Studies on 3-Hydroxyanthranilate-3,4-dioxygenase: The Catalytic Mechanism of a Complex Oxidation Involved in NAD Biosynthesis.
Zhang, Y., Colabroy, K.L., Begley, T.P., Ealick, S.E.
Biochemistry