CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.1600 | SIR2/SIRT2 'Small Domain' |
|
3.30.1600.10 | SIR2/SIRT2 'Small Domain' |
Domain Context
CATH Clusters
| Superfamily | SIR2/SIRT2 'Small Domain' |
| Functional Family |
Enzyme Information
| 3.5.1.- |
In linear amides.
based on mapping to UniProt O30124
|
UniProtKB Entries (1)
| O30124 |
NPD2_ARCFU
Archaeoglobus fulgidus DSM 4304
NAD-dependent protein deacylase 2
|
PDB Structure
| PDB | 1YC2 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Mechanism of Sirtuin Inhibition by Nicotinamide: Altering the NAD(+) Cosubstrate Specificity of a Sir2 Enzyme.
Mol.Cell
|