CATH Classification

Domain Context

CATH Clusters

Superfamily TPP-binding domain
Functional Family NAD-dependent protein deacylase 1

Enzyme Information

3.5.1.-
In linear amides.
based on mapping to UniProt O30124

UniProtKB Entries (1)

O30124
NPD2_ARCFU
Archaeoglobus fulgidus DSM 4304
NAD-dependent protein deacylase 2

PDB Structure

PDB 1YC2
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Mechanism of Sirtuin Inhibition by Nicotinamide: Altering the NAD(+) Cosubstrate Specificity of a Sir2 Enzyme.
Avalos, J.L., Bever, K.M., Wolberger, C.
Mol.Cell