CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family

Enzyme Information

1.1.1.80
Isopropanol dehydrogenase (NADP(+)).
based on mapping to UniProt P35630
Propan-2-ol + NADP(+) = acetone + NADPH.
-!- Also acts on other short-chain secondary alcohols and, slowly, on primary alcohols.

UniProtKB Entries (1)

P35630
ADH1_ENTHI
Entamoeba histolytica
NADP-dependent isopropanol dehydrogenase

PDB Structure

PDB 1Y9A
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of alcohol dehydrogenase from Entamoeba histolytica.
Shimon, L.J., Goihberg, E., Peretz, M., Burstein, Y., Frolow, F.
Acta Crystallogr.,Sect.D