CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.1100
Functional Family Cysteine synthase

Enzyme Information

2.5.1.47
Cysteine synthase.
based on mapping to UniProt P45040
O-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate.
-!- Some alkyl thiols, cyanide, pyrazole and some other heterocyclic compounds can act as acceptors. -!- Not identical with EC 2.5.1.51, EC 2.5.1.52 and EC 2.5.1.53. -!- Formerly EC 4.2.99.8.

UniProtKB Entries (1)

P45040
CYSK_HAEIN
Haemophilus influenzae Rd KW20
Cysteine synthase

PDB Structure

PDB 1Y7L
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The active site of O-acetylserine sulfhydrylase is the anchor point for bienzyme complex formation with serine acetyltransferase.
Huang, B., Vetting, M.W., Roderick, S.L.
J.Bacteriol.