CATH Classification

Domain Context

CATH Clusters

Superfamily Phospholipase A2 domain
Functional Family

Enzyme Information

3.1.1.4
Phospholipase A(2).
based on mapping to UniProt P00592
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.
-!- Also acts on phosphatidylethanolamine, choline plasmalogen and phosphatides, removing the fatty acid attached to the 2-position.

UniProtKB Entries (1)

P00592
PA21B_PIG
Sus scrofa
Phospholipase A2, major isoenzyme

PDB Structure

PDB 1Y6O
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Kinetic and structural properties of disulfide engineered phospholipase a(2): insight into the role of disulfide bonding patterns.
Yu, B.Z., Pan, Y.H., Janssen, M.J.W., Bahnson, B.J., Jain, M.K.
Biochemistry