CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleoside phosphorylase domain
Functional Family Uridine phosphorylase

Enzyme Information

2.4.2.3
Uridine phosphorylase.
based on mapping to UniProt P0A1F6
Uridine + phosphate = uracil + alpha-D-ribose 1-phosphate.
-!- The enzyme participates the the pathways of pyrimidine ribonucleosides degradation and salvage. -!- The mammalian enzyme also accepts 2'-deoxyuridine. -!- Formerly EC 2.4.2.23.

UniProtKB Entries (1)

P0A1F6
UDP_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Uridine phosphorylase

PDB Structure

PDB 1Y1R
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal Structures of Salmonella Typhimurium Uridine Phosphorylase in Complex with Inhibitor and Phosphate.
Dontsova, M.V., Gabdoulkhakov, A.G., Kachalova, G.S., Betzel, C., Ealick, S.E., Mikhailov, A.M.
To be Published