CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.420.40
Functional Family Glycerol kinase

Enzyme Information

2.7.1.30
Glycerol kinase.
based on mapping to UniProt O34153
ATP + glycerol = ADP + sn-glycerol 3-phosphate.
-!- Glycerone and L-glyceraldehyde can act as acceptors. -!- UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors.

UniProtKB Entries (1)

O34153
GLPK_ENTCA
Enterococcus casseliflavus
Glycerol kinase

PDB Structure

PDB 1XUP
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structures of Enterococcal Glycerol Kinase in the Absence and Presence of Glycerol: Correlation of Conformation to Substrate Binding and a Mechanism of Activation by Phosphorylation
Yeh, J.I., Charrier, V., Paulo, J., Hou, L., Darbon, E., Clairborn, A., Hol, W.G.J., Deutscher, J.
Biochemistry