CATH Classification

Domain Context

CATH Clusters

Superfamily 5'-nuclease
Functional Family

Enzyme Information

3.1.11.3
Exodeoxyribonuclease (lambda-induced).
based on mapping to UniProt P06229
Exonucleolytic cleavage in the 5'- to 3'-direction to yield nucleoside 5'-phosphates.
-!- Preference for double-stranded DNA. -!- Does not attack single-strand breaks. -!- Similar enzymes: T4, T5 and T7 exonucleases, mammalian DNase IV. -!- Formerly EC 3.1.4.28.
3.1.11.-
Exodeoxyribonucleases producing 5'-phosphomonoesters.
based on mapping to UniProt P06229

UniProtKB Entries (1)

P06229
EXO5_BPT5
Escherichia virus T5
T5 flap endonuclease

PDB Structure

PDB 1XO1
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Mutagenesis of conserved lysine residues in bacteriophage T5 5'-3' exonuclease suggests separate mechanisms of endo-and exonucleolytic cleavage.
Garforth, S.J., Ceska, T.A., Suck, D., Sayers, J.R.
Proc.Natl.Acad.Sci.USA